Alternatives to antibiotics

The use of antibiotic growth promoters in food-producing animals has emerged as a cause of antimicrobial resistance and thereby a potential threat to humans, demanding urgent attention towards discovering novel and safe anti-infectives. Extracts and their compounds derived from plants used in ethnoveterinary practice are considered prospective sources for developing alternatives to these agents. Despite the rich evidence of the use of plants in the treatment of diarrhoeal infections in farm animals in ethnoveterinary practice in India, there are scarce studies that confirm their antimicrobial efficiency. Therefore, the work aims to evaluate in vitro antimicrobial activity of extracts from plants used in ethnoveterinary medicine in India to treat diarrhoea and dysentery in livestock using the broth microdilution method. These studies might be useful in search of the substituents of antibiotic growth promoters for food-producing animals and animal health and welfare.

Published by

Dhiraj Jain

Dhiraj received his Bachelor in Pharmacy (B. Pharma) with distinction from Pune University, India and Master of Science (M. Sc.) with merit from Technical University Munich, Germany. After graduation, he started to work part-time in this field at saqual GmbH, Switzerland. Since October 2008, he is working as an independent assistant consultant to various clients. His work focuses on herbs and botanicals to be used in food, feed, pharmaceuticals and Ayurvedic products; mainly, literature review, scientific writing, technical documentation; secondly, preliminary assessment reports, scientific papers; thirdly, preliminary opinions on safety, efficacy and quality; and preparation of detailed dossiers in formats accepted by different regulatory bodies.